A red desert landscape with sparse vegetation and a clear blue sky.
Photo by Melissa Shea
Open Photo by Melissa Shea

Northwest Oklahoma Vacations from $537

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Your Northwest Oklahoma Vacation

When wanderlust beckons, answer it with a vacation package to Northwest Oklahoma. Get set to experience walking trails, views, nature, and more in this vibrant destination. Your trip to Northwest Oklahoma wouldn't be complete without exploring some of its best cities, starting with Enid. A couple of the top attractions here include Leonardo's Children's Museum and Adventure Quest and Railroad Museum of Oklahoma. Guymon is another favorite with Northwest Oklahoma travelers. Visitors to this city love North Ridge Shopping Center and Wild Horse Gallery. Start packing your bags, because your Northwest Oklahoma vacation is only a few clicks away with Expedia.

The Latest Northwest Oklahoma Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 15 - Jan 18

    Wyndham Grand Oklahoma City Downtown + Flight

    Downtown Oklahoma City
    3 nights
    4.0 star property
    8.0/10 - Very good (3,501 reviews)
    "There were not enough outlets in the room,"
    Reviewed November 9, 2026
    Roundtrip • Detroit (DTW) - Oklahoma City (OKC)
    DTW - OKC • 1 stop OKC - DTW • 1 stop
    $611
    $537
    per traveler
    found 5 hours ago
    Wyndham Grand Oklahoma City Downtown
  • Jan 15 - Jan 18

    Sheraton Oklahoma City Downtown Hotel + Flight

    Downtown Oklahoma City
    3 nights
    4.0 star property
    9.2/10 - Wonderful (1,505 reviews)
    "The property was generally clean. It’s seems older and there were quite a few water damage repairs around the building. The staff were very kind and helpful. My issue is that the building smelled of mildew and smoke. The lobby seemed fine and it was very cool in there like it had a filtration system, but my room was very stinky and muggy. Every time I used the sink in the bathroom it filled the entire room with a horrible mold and mildew smell. I had to keep a towel on it if I wasn’t using..."
    Reviewed November 9, 2026
    Roundtrip • Detroit (DTW) - Oklahoma City (OKC)
    DTW - OKC • 1 stop OKC - DTW • 1 stop
    $692
    $577
    per traveler
    found 5 hours ago
    Sheraton Oklahoma City Downtown Hotel
  • Dec 26 - Dec 30

    Fordson Hotel, in the Unbound Collection by Hyatt + Flight

    Downtown Oklahoma City
    4 nights
    4.0 star property
    9.4/10 - Exceptional (1,001 reviews)
    Roundtrip • Detroit (DTW) - Oklahoma City (OKC)
    DTW - OKC • 1 stop OKC - DTW • 1 stop
    $890
    $768
    per traveler
    found 11 hours ago
    Fordson Hotel, in the Unbound Collection by Hyatt
  • Dec 26 - Dec 30

    Renaissance Waterford Oklahoma City Hotel + Flight

    Central Oklahoma City
    4 nights
    4.0 star property
    8.6/10 - Excellent (1,007 reviews)
    "Hotel was lovely. Rooms are a little worn but clean and nice. Just a little older. Still nice hotel and quiet. In a very nice area."
    Reviewed November 9, 2026
    Roundtrip • Detroit (DTW) - Oklahoma City (OKC)
    DTW - OKC • 1 stop OKC - DTW • 1 stop
    $760
    $663
    per traveler
    found 11 hours ago
    Renaissance Waterford Oklahoma City Hotel
  • Dec 26 - Dec 30

    Ambassador Hotel Oklahoma City, Autograph Collection + Flight

    Downtown Oklahoma City
    4 nights
    4.5 star property
    9.6/10 - Exceptional (616 reviews)
    Roundtrip • Detroit (DTW) - Oklahoma City (OKC)
    DTW - OKC • 1 stop OKC - DTW • 1 stop
    $902
    $814
    per traveler
    found 13 hours ago
    Ambassador Hotel Oklahoma City, Autograph Collection

Discover the most popular places to visit in Northwest Oklahoma

Northwest Oklahoma Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.